If you've never tried retinol or have and experienced irritation, then the CosMedix Serum 16 is the serum for you. Powered by the CosMedix Microencapsulated Retinol Complex, this nightly treatment reduces the depth of lines and wrinkles without causing redness, dryness or irritation. By coupling hydrators with retinol this serum targets the causes of aging without drying out skin. In fact, this formula fortifies your skin's moisture barrier to ensure your skin stays properly hydrated throughout the night. Beneficial to all skin types, even sensitive and those that traditionally cannot tolerate retinol treatments. Calm acne inflammation, combat wrinkle formation, even skin tone and boost moisture all while you slumber. Bottle provides approximately 90 applications with regular use. Key Ingredients and Benefits: 16% LG-Retinex (Microencapsulated Retinol Complex): reduces the appearance of lines and wrinkles Sodium PCA and Squalane: hydrates and prevents moisture loss Vitamin E: protects skin from free-radical damage | COSMEDIX Serum 16 Rapid Renewal Serum, 1 oz | Dermstore