Gentle enough to use twice a day, and carefully calibrated for both immediate and long-term results, Daily Rejuvenating Cream delivers a dose of essential hydration that lasts up to 10 hours after use. In addition to the line-smoothing retinol and microbiome support of Time Retreat Complex, this formula also features Epidermosil (a low-molecular-weight hyaluronic acid blended with silicium) and a wild indigo seed extract called neurophroline, known to activate the release of calming neuropeptides.